Sterile vial filling

We offer extensive support for this trusted and proven injectable product format. Explore the flexible configurations we can process, our state-of-the-art filling facilities, and expert approach to aseptic vial filling.

Sterile vial filling
Flüssig-Vials nach der sterilen Abfüllung

Deep expertise in an essential format

As a global leader in aseptic fill-finish for injectable products, we offer world-class filling services for vial-based products. Our support spans a wide range of vial configurations and fill volumes, as well as complex molecules and substance classes.

At our sterile vial filling facilities in the US and EU, you’ll find flexible capacity to suit every stage in the injectable product life cycle. Our cGMP-compliant sites are designed to manage sterile vial filling (bulk & pre-sterilized) at the highest possible quality levels, using state-of-the-art components, pumps, and more.

Key steps in vial filling (bulk)

Vials getting washed in washing machine
Washing
Vials enter dry heat tunnel for sterilization
Sterilization
Vial filling
Sterile vial filling
Stopper being placed
Stopper placement
Lyophilization of Vials
Lyophilization (optional)
Vial capping
Capping
Visual inspection of filled Vials
Visual inspection
Aseptischer Reinraum mit Vial-Linie
Vetter Development Service

Sterile vial filling for clinical products

Our cutting-edge clinical manufacturing sites in Chicago, Rankweil, and Ravensburg are all fully equipped to produce clinical trial material in both liquid and lyophilized vials.

Technical capabilities

  • cGMP aseptic vial filling
  • RABS for maximum process security
  • 100% inline weight control for non-destructive IPC
  • CIP/SIP lyophilizer

 

Vetter Development Service Chicago: Early-stage clinical
Vetter development service office in Chicago, USA

Equipment:

Filling unit for liquid and lyophilized vials

Formats:

2R, 6R, 10R, 20R, 25R

Fill volume:

Range: 0.3-28.9 mL

More Details

Vetter Development Service Rankweil: Early-stage clinical
Clinical manufacturing facility in Rankweil

Equipment:

Filling unit for liquid and lyophilized vials

Formats:

2R, 6R, 10R, 20R

Fill volume:

Range: 0.3-20.0 mL

More Details

Vetter Development Service Ravensburg: Late-stage clinical
Vetter development service office in Ravensburg, Germany

Equipment:

Multiple filling units for liquid and lyophilized vials

Formats:

2R, 6R, 10R, 20R, 25R, 50R

Fill volume:

Range: 0.1ml - 50.0 mL

Man holding and inspecting a filled liquid vial

Commercial-scale sterile vial filling

Together, our Ravensburg Vetter South and Vetter Langenargen facilities offer multiple aseptic vial filling lines.

Technical capabilities

  • cGMP aseptic filling at global scale
  • 100% visual inspection (manual or automated)
Ravensburg Vetter Süd (RVS) & Vetter Langenargen (VLA)

Equipment:

Multiple filling units for liquied and lyophilized Vials

Closure system:

Flip-off caps, crimp caps

Fill volume:

Range: 0.1ml - 50.0 mL

Formats:

2R, 6R, 10R, 20R, 25R, 50R

Details about RVS

Details about VLA

John Moore contact

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Want to learn more about our vial filling services? Reach out to our team to discuss how we can support you.

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