sWFI syringe 1.5 ml
The world biologics market continues to rise and is expected to reach 250 billion $ in 2024.1 The introduction of new biologics increases the demand for lyophilized drugs, due to the unstable nature and limited shelf life of many biopharmaceutical compounds. Given the ever increasing costs of drug development and the rapidly increasing launch of parenteral lyophilized products, it is even more fundamental to make decisions not only about the compound, but also about the diluent. Most importantly the diluent as part of the drug package should not affect or influence the efficacy of the drug.
There are several diluent delivery options available on the market today including vials, prefilled syringes, or dual-chamber syringes. Traditional reconstitution requires a number of components: 2 vials (1 with the lyophilized drug and 1 with a diluent), a disposable syringe, and 2 needles. Most importantly it also requires experience and training and carries the risk of a needle stick injury to the person administering the drug. Prefilled diluent syringes come with a number of distinct advantages. Prefilled syringes eliminate components and process steps used in traditional reconstitution, thereby reducing risks and opening up new opportunities for the product. These self-contained systems are simple and safe for patients to use – they minimize handling, decrease the potential for dosing errors, maintain a stable pH value, and even help protect against tampering.
Advantages of prefilled diluent syringes:
Prefilled syringes or dual-chamber diluent options can also assist in product differentiation when a drug maker is looking to expand the market for their product.